MED4 Antibody, FITC conjugated

Code CSB-PA865098LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MED4 Polyclonal antibody
Uniprot No.
Target Names
MED4
Alternative Names
Activator-recruited cofactor 36 kDa component antibody; ARC36 antibody; DRIP36 antibody; FLJ10956 antibody; HSPC126 antibody; med4 antibody; MED4_HUMAN antibody; Mediator complex subunit 4 antibody; Mediator of RNA polymerase II transcription subunit 4 antibody; Mediator of RNA polymerase II transcription, subunit 4 homolog antibody; OTTHUMP00000018390 antibody; OTTHUMP00000018391 antibody; OTTHUMP00000018392 antibody; RP11-90M2.2 antibody; TRAP/SMCC/PC2 subunit p36 subunit antibody; TRAP36 antibody; VDRIP antibody; Vitamin D3 receptor-interacting protein complex 36 kDa component antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Mediator of RNA polymerase II transcription subunit 4 protein (167-270AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Gene References into Functions
  1. retinoblastoma RB1 -/- cells cannot survive in the absence of MED4, both in vitro and in orthotopic xenograft models in vivo, therefore identifying MED4 as a survival gene in retinoblastoma. PMID: 24858910
  2. Our findings suggest that Vitamin D Receptor polymorphisms may be associated with nasal carriage of S. aureus in individuals with type 1 diabetes. PMID: 19411183
Subcellular Location
Nucleus.
Protein Families
Mediator complex subunit 4 family
Database Links

HGNC: 17903

OMIM: 605718

KEGG: hsa:29079

STRING: 9606.ENSP00000258648

UniGene: Hs.181112

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